Presence of an abnormal monoclonal protein (M protein) in blood without signs of cancer (pre-malignant condition)
The key distinction in the rating criteria is whether your condition is symptomatic or asymptomatic. Medical records that document active symptoms of multiple myeloma — such as bone lesions, kidney problems, elevated calcium, or anemia tied to the disease — support a finding of symptomatic disease at the 100% level. Records showing no such symptoms, or a diagnosis specifically of smoldering multiple myeloma or MGUS, point toward the 0% level.
The regulation allows diagnosis to be supported by current validated biomarkers as recognized by the American Society of Hematology and the International Myeloma Working Group. Lab results, bone marrow biopsy reports, imaging studies, and treating physician notes that reflect these biomarkers and your symptom status are all relevant. Statements from you or people who know you about how symptoms affect your daily life and ability to work can also help show the severity of your condition at any point in time.
Conditions that are often caused or made worse by this one. If you have any of these, they may be claimable as secondary service connection.
